Generic PravacholPravastatin 10/20mg | |||||||||||||||||||||||||||||||||||||||||
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Generic Pravachol (Pravastatin 10/20mg)
Pravachol
Pravastatin Sodium
Primary hypercholesterinemia (apart from a familial homozygotic one) predominantly of types IIa and IIb (if dietotherapy has proven to be non-efficient in patients with an enhanced risk of emerging of coronary atherosclerosis), hypercholisterinemia in combination with hypertriglyceridemia; prevention measures for ischemic heart disease (decrease of the risk of myocardial infarction, necessity of myocardial revasculization surgery, prevention measures for cardial vascular diseases mortality).
Pravastatin Sodium is medication which is used to deflate an enhanced level of cholesterin in blood.
The drug should be taken orally regardless of meal; the starting dose should be 10-20 mg single-shot, before sleep. In significant increase of cholesterin concentration in plasma (more than 300 mg/dl) the starting dose should be increased up to 40 mg once daily before sleep. Maximal therapeutic effect will be manifested during 4 weeks from the start of treatment. In this period a dose correction in relation to time course of lipid concentration in plasma should be done. In liver or kidneys failure the starting dose should not exceed 10 mg., for elderly patients a dose of 20 mg/daily usually is efficient.
Hypersensitivity, liver diseases and/or compromised liver function, pregnancy, breastfeeding, childhood, adolescence and teen-age (under 18 years of age).
During the treatment liver function monitoring is necessary.
Without a special order of a doctor do not use Pravastatin Sodium together with other medications.
There was information about two cases of overdosing – the cases were manifested only with changes of biochemical blood analysis. The treatment should be symptomatic.
Dysfunction of cranial nerves (disorder of sense of taste, not-willed movements of eyes), not-willed movements of limbs, dizziness, psychic tension, insomnia, depression, pancreatitis, hepatitis, hepatic cirrhosis or necrosis, liver malignant tumor, significant loss of weight because of abnormal loss of appetite, nausea, pains in muscles, acute kidneys failure, pains in mammary glands, deflation of libido and potency, progression of cataract, skin pigmentation, dry skin and mucus coatings, breathing trouble, hypersensitivity to the sun light, allergic reactions (allergic shock, angioedema, hives).
Pravastatin Sodium is counterindicated in pregnancy. During the treatment breastfeeding should be stopped.
In the starting (individually determined) period of the drug use it is prohibited to drive vehicles or to carry out trauma dangerous works. A degree of forbiddenness will be determined in each specific case.
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