Generic Zerit

1. Denomination
Zerit

2. Active Substance

Stavudine

3. Indications for Use.

Stavudine is an antivirus remedy for the treatment of HIV-positive patients (it possesses anti-HIV activity)

4. Action

HIV-infection (including that of after Zidovudine therapy).

5. Posology and Administration

A usual single-shot dose for adults and the children whose body mass exceeds 30 kg is 30 mg; for patients with the body mass of 60 kg and more a dose will be 40 mg. A daily dose should be divided into two intakes, usually with 12-hours break between intakes (30 or 40 mg twice daily).
Children of more than 3 months of age, whose body does not exceed 30 kg should receive a Stavudine dose 1 mg/kg twice daily, in case if the body mass is big an adult dosage rate should be used for them.
In cases of poly-neuropathy and the increase of hepatic ferments activity Stavudine therapy should be withdrawn. After side effects have disappeared the therapy will be resumed in a lesser dose: less than 60 kg: 15 mg twice a day; more than 60 kg: 20 mg twice a day.
In evidenced compromised kidneys function a Stavudine dose should be decreased in compliance with CK indications.
For the optimum blotting capacity it is well to take Stavudine at least one hour before meal. If it is not possible you may take the drug together with delicate food.
The time duration of administration should be determined by a doctor on an individual basis. Usually it is used in a long-term therapy (up to 2 years).
If you incidentally skip a contact with the drug, next time you should take your usual dose. Do not take a double dose to compensate the omitted one.

6. Counterindications

-  peripheral neuropathy;
-  severe compromised kidneys functions;
-  severe compromised liver functions;  
-  hypersensitivity to Stavudine or to any auxiliary component of the drug.

7. Should Be Taken with Precautions, if…

During Stavudine therapy the patient should be under a doctor’s supervision.
With caution it should be used in sufferers of compromised liver and kidneys function, with nerve injury and pancreatitis.
Strict precautions should be continued in order not to infect other people
Nowadays there are no true information on the use of Stavudine in children of less than 3 months of age.
Information for diabetes patients: 1 ml of a prepared solution of Stavudine contains 50 mg of saccharose.

8. Interface with Other Medications

Do not use Stavudine in combination with the medicines not recommended by a doctor, there is a risk of adverse interaction of the drugs.

9. Overdosing

If you have taken too much solution of the drug or if somebody (for instance, a child) incidentally has swallowed a good few of Stavudine it is not of a great risk. But for more confidence you should visit a doctor or the nearest health care facility for consultation.

10. Side Effects

While therapy of HIV-positive patients it is not an easy task to draw a clear boundary between the side effects provoked with Stavudine administration or the side effects of other medications which are taken simultaneously, and merely adverse symptoms conditioned by complexity of the disease.
On the part of CNS: sensation of numbness or feeling of acute burning in feet, legs or arms, headache, dizziness, lack of energy, weakness, insomnia.
On the part of digestive system: dry mouth, pains in stomach, nausea, vomit, loss of appetite and, as a consequence, weight loss, diarrhea or constipation, liver disorder, pancreatitis.
On the part of musculoskeletal system: muscular and joint pains (athralgia, myalgia).
Blood compositional disorder.
Allergic reactions: skin rash.
Others: panting, respiratory infections, feverish states, pains in breast.

11. Pregnancy  and Lactation

Stavudine may be taken during pregnancy only on absolute indications, after evaluation of a supposed favor for the mother and a potential risk for the fetus, under a doctor’s supervision. If there is a need to use the drug in the period of lactation breastfeeding should be stopped. There is a professional recommendation to HIV-positive patients to give up on breastfeeding in any case in order avoiding danger of introduction of infection to the baby.

12. Driving

Due to the drop of reaction rate it is not recommended to drive vehicles or to operate machinery.

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Q. How do I cancel my order of Generic Zerit ( Stavudine 40mg ) ?
A. Refund Policy

Q. Can you tell me if I should be taking Generic Zerit ( Stavudine 40mg ) ? Or, will it work for me?
A. We cannot advise you in any capacity in this matter. You should not take any medication without consulting a physician first.

Q. What is your returns policy?
A. By law, we regret that we are unable to accept returned pharmaceuticals. If your purchase is defective in any way, we will be pleased to replace it at no cost to you.

Q. What about importing of Generic Zerit ( Stavudine 40mg ) to my country ?
A. Importation of prescription medication is legal in most countries (including the US, UK, France, Spain, Hong Kong, Japan and S. Korea) provided the medication is for personal use and is not a controlled substance. If you are in doubt about the situation in your country, check with your local Post Office.