Tag: narrow therapeutic index drugs

Dose Adjustments After Switching to Generics: When Doctors Change Doses

Switching to generic medications is common, but for Narrow Therapeutic Index (NTI) drugs, it can require dose adjustments. Learn why bioequivalence doesn't always mean clinical equivalence and how doctors monitor for necessary changes.

NTI Substitution Laws: Which States Ban or Restrict Generic Drug Swaps

Twenty-seven U.S. states have special rules restricting generic substitution for narrow therapeutic index drugs like warfarin, levothyroxine, and lithium. Learn which states block swaps, require consent, or allow changes - and what it means for your health.